Pentaethylene glycol

CAS No. 4792-15-8

Pentaethylene glycol( —— )

Catalog No. M33460 CAS No. 4792-15-8

Pentaethylene glycol (3,6,9,12-Tetraoxatetradecane-1,14-diol) is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Pentaethylene glycol
  • Note
    Research use only, not for human use.
  • Brief Description
    Pentaethylene glycol (3,6,9,12-Tetraoxatetradecane-1,14-diol) is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
  • Description
    Pentaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    PROTAC
  • Recptor
    PROTAC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    4792-15-8
  • Formula Weight
    238.28
  • Molecular Formula
    C10H22O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OCCOCCOCCOCCOCCO
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
molnova catalog
related products
  • Amino-PEG11-amine

    Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.

  • tert-Butyl 11-aminou...

    tert-Butyl 11-aminoundecanoate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

  • DD-03-171

    DD-03-171 is a small molecule, CGI1746-based BTK degrader (PROTAC, biochemical IC50=5.1 nM) that efficiently degrade C481S-BTK.